Can I take Alcohol and Rosuvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
- Add to preferred sources on Google
Drinking alcohol while taking rosuvastatin can increase the risk of liver problems and a rare but serious muscle condition called rhabdomyolysis. While a small amount of alcohol is usually fine, heavy or regular drinking makes side effects much more likely.
Why this happens
Both alcohol and rosuvastatin are processed by the liver. Alcohol can cause inflammation or damage to liver cells, which may prevent the liver from clearing the medication properly. Additionally, both substances can independently cause muscle toxicity; when combined, this effect can be worsened.
What you should do
It is best to limit your alcohol intake while taking rosuvastatin. Avoid 'binge drinking' and stay within the recommended UK low-risk guidelines (no more than 14 units per week). If you have a history of liver disease or heavy alcohol use, speak to your doctor before starting this medication. Seek medical help immediately if you experience unexplained muscle pain, tenderness, or weakness.
Important precautions
Pregnancy
You must not take rosuvastatin if you are pregnant or trying to conceive, as it may harm the developing baby. Use effective contraception while taking this medicine.
Excessive alcohol consumption
Regularly drinking large amounts of alcohol while taking rosuvastatin significantly increases your risk of serious liver problems and muscle damage (rhabdomyolysis).
Unexplained muscle pain - rosuvastatin
You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can be a sign of rare but life-threatening muscle breakdown.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Mounjaro and Insulin together?
Taking Mounjaro (tirzepatide) and insulin together significantly increases your risk of having a 'hypo' (hypoglycaemia), which is when your blood sugar levels drop too low. Symptoms of a hypo can include feeling shaky, sweaty, dizzy, hungry, or confused. In severe cases, it can be dangerous.

Drug interactions checker
Can I take Allopurinol and Nortriptyline together?
There is no known direct interaction between allopurinol and nortriptyline. However, both medications can occasionally cause side effects that affect the liver or blood counts. Taking them together does not typically increase these risks, but it is important to be aware of how you feel.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.
More in drug interactions checker
- Can I take Alcohol and Atorvastatin together?
- Can I take Ashwagandha and Oestrogel pump-pack together?
- Can I take Atenolol and Ramipril together?
- Can I take Atorvastatin and Colecalciferol together?
- Can I take Cordyceps and Shiitake together?
- Can I take Folic acid and Vitamin B2 together?
- Can I take Glucosamine and Solifenacin together?
- Can I take Lansoprazole and Quetiapine together?
- Can I take Levothyroxine and Liothyronine together?
- Can I take Levothyroxine and Prednisolone together?
- Can I take Levothyroxine and Simvastatin together?
- Can I take Lion's mane and Shiitake together?
- Can I take Losartan and Tizanidine together?
- Can I take Magnesium and Simvastatin together?
- Can I take Mounjaro and Metformin together?
- Can I take Pancreatin and Solifenacin together?
- Can I take Pregabalin and Vitamin D together?
- Can I take Pregabalin and Wellbutrin together?
- Can I take Warfarin and Methotrexate together?
- Can I take Warfarin and Paracetamol together?