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Can I take Alogliptin and Losartin together?

Drug interaction guide

Taking alogliptin and losartan together may slightly increase the risk of your blood sugar levels dropping too low (hypoglycaemia). It may also increase the risk of a rare but serious allergic reaction called angioedema (swelling of the face, lips, or throat).

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Why this happens

Alogliptin helps lower blood sugar, and some blood pressure medications like losartan can occasionally enhance this effect. Additionally, both drugs can affect a system in the body that regulates swelling, which may rarely lead to an allergic-type reaction.

What you should do

It is generally safe to take these together, but you should monitor your blood sugar levels more closely, especially when starting or changing doses. Seek immediate medical help if you notice any swelling of the face, lips, or tongue, or if you have difficulty breathing.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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