Can I take Amitriptyline and Bisoprolol together?

Why this happens

Both medicines have effects on the heart and blood vessels. Bisoprolol is a beta-blocker designed to slow the heart and lower blood pressure. Amitriptyline, while an antidepressant, can also affect heart rhythms and blood pressure. When used together, these effects can add up (an additive effect).

You can usually take these together, but you should be monitored by your doctor. When starting this combination or changing doses, move slowly when standing up from a sitting or lying position to avoid dizziness. If you feel very dizzy, faint, or notice an unusually slow or irregular heartbeat, contact your doctor.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.