Can I take Amitriptyline and Concerta together?

Why this happens

Both drugs increase the levels of certain chemicals in the brain and body, such as norepinephrine and serotonin. When combined, their effects on the heart and nervous system can add up. Additionally, amitriptyline may slow down how the body breaks down methylphenidate, leading to higher levels of the drug in your system.

You should only take these two medications together if they have been specifically prescribed by your doctor with knowledge of both. Your doctor should monitor your blood pressure and heart rate regularly. Seek medical help immediately if you experience chest pain, palpitations, a very fast heartbeat, severe headaches, or confusion.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.