Can I take Amitriptyline and Doxazosin together?

Why this happens

Both medicines have the effect of relaxing your blood vessels and lowering blood pressure. When used together, this effect is 'additive' (they add together to become stronger). Additionally, both drugs can cause drowsiness, which is increased when they are combined.

You should speak to your doctor before taking these together. If you are already taking both, be very careful when moving from a lying or sitting position to standing up—do it slowly to avoid dizziness. It is best to take these medicines at bedtime. Avoid driving or using machinery until you know how this combination affects you. If you feel very dizzy or faint, contact your doctor.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.