Can I take Amlodipine and Ozempic together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
While there is no direct 'clash' between these two medicines, Ozempic can sometimes cause a slight increase in heart rate or changes in blood pressure. Since amlodipine is used to lower blood pressure, the combination might occasionally lead to your blood pressure dropping a bit lower than intended, or you might feel slightly dizzy when standing up. Additionally, Ozempic slows down how quickly your stomach empties, which can theoretically change how other tablets are absorbed, though this rarely causes issues with amlodipine.
In this article:
Continue reading below
Why this happens
Ozempic (semaglutide) mimics a hormone that slows gastric emptying (how fast food and pills leave the stomach). This can alter the timing of how amlodipine enters your system. Furthermore, both drugs can affect the cardiovascular system in different ways—amlodipine relaxes blood vessels to lower pressure, while Ozempic can slightly increase heart rate.
What you should do
Back to contentsYou can generally take these two medicines together safely. However, you should monitor your blood pressure regularly at home, especially when you first start Ozempic or when your dose is increased. If you feel dizzy, lightheaded, or faint, speak to your doctor, as they may need to adjust your blood pressure medication.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take Abilify and Fluoxetine together?
Taking fluoxetine with Abilify (aripiprazole) can significantly increase the amount of Abilify in your bloodstream. This makes you much more likely to experience side effects such as extreme sleepiness, restlessness (feeling like you cannot sit still), uncontrollable body movements (tremors or twitching), and dizziness. There is also a small but serious risk of a heart rhythm problem called QT prolongation.
Treatment and medication
Can I take Ashwagandha and Vitamin d2 together?
There are no known significant interactions between ashwagandha and vitamin D2 (ergocalciferol). It is generally considered safe to take these two supplements together.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.