Can I take Amlodopine and Apixaban together?

Why this happens

Both drugs are processed by the same enzyme in the liver (CYP3A4) and a transport protein (P-gp). Amlodipine can slightly slow down how quickly the body clears apixaban, leading to a minor increase in the amount of apixaban in your system.

What you should do

You can usually take these medicines together, but you should be aware of the signs of bleeding. Contact your doctor if you notice unusual bruising, nosebleeds, bleeding gums, or blood in your urine or stools. Do not stop taking either medication without consulting your healthcare provider.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.