Skip to main content

Can I take Amlodopine and Atorvastatin together?

Drug interaction guide

Taking these two medicines together can increase the amount of atorvastatin in your blood. This may increase the risk of side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In very rare cases, this can lead to a serious kidney problem called rhabdomyolysis.

Continue reading below

Why this happens

Amlodipine can slow down the process by which your liver breaks down atorvastatin. Because the liver is busy processing the amlodipine, the atorvastatin stays in your system longer and reaches higher levels than intended.

What you should do

It is common for these drugs to be prescribed together, but your doctor may choose to limit your dose of atorvastatin (usually to no more than 20mg or 40mg daily) to keep you safe. If you experience any unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or feel generally unwell—contact your doctor immediately.

Continue reading below

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.