Can I take Amlodopine and Fibre supplements together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking fibre supplements at the same time as amlodipine may slightly lower the amount of medicine your body absorbs. This could potentially make the blood pressure medication less effective.
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Why this happens
Soluble fibre can bind to medications in the digestive tract or slow down the rate at which the stomach empties. This can interfere with how well the amlodipine is absorbed into your bloodstream.
What you should do
You do not need to stop taking fibre, but you should try to space them out. Take your amlodipine at least 2 hours before or 4 to 6 hours after taking a fibre supplement (such as psyllium husk, Fybogel, or methylcellulose). Monitor your blood pressure regularly to ensure it remains stable.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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