Skip to main content

Can I take Amlopidine and Magnesium together?

Drug interaction guide

Taking amlodipine and magnesium together may cause your blood pressure to drop lower than intended. This can lead to symptoms like dizziness, lightheadedness, or feeling faint. In some cases, it may also cause a very slow or irregular heartbeat.

Continue reading below

Why this happens

Both amlodipine and magnesium work by relaxing the muscles in your blood vessels and heart. Amlodipine is a 'calcium channel blocker', and magnesium acts as a natural calcium blocker. When used together, they can have an 'additive effect', meaning they strengthen each other's ability to lower blood pressure and slow the heart.

It is usually safe to take these together, but you should monitor your blood pressure regularly. If you feel dizzy, especially when standing up, or notice your heart rate is unusually slow, speak to your GP. If you are taking high-dose magnesium supplements or using magnesium intravenously, your doctor may need to adjust your amlodipine dose.

Continue reading below

Kidney disease

If you have severe kidney impairment, your body cannot remove excess magnesium. This can lead to dangerously high levels in the blood, affecting your heart rhythm and breathing.

Dairy products (Milk, Cheese, Yoghurt)

Dairy products are high in calcium. Calcium can compete with magnesium for absorption in the gut. If you take a magnesium supplement, try to take it at least 2 hours apart from eating large amounts of dairy to ensure you get the full benefit of the mineral.

Alcohol

Alcohol can lower your blood pressure. Taking amlodipine with alcohol may cause you to feel dizzy, lightheaded, or faint. Additionally, chronic alcohol consumption can cause the body to lose magnesium through urine, potentially making a magnesium deficiency worse.

Continue reading below

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.