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Can I take Aspirin 300 and Quetiamine together?

Drug interaction guide

Taking aspirin and quetiapine together may increase your risk of bleeding, particularly in the stomach or gut. It can also increase the risk of feeling dizzy or faint when you stand up.

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Why this happens

Aspirin thins the blood and can irritate the stomach lining, while quetiapine can sometimes interfere with how platelets (the cells that help blood clot) work. Additionally, both medications can cause a drop in blood pressure when standing, which may lead to dizziness.

What you should do

You should use this combination with caution. Watch for signs of unusual bleeding, such as easy bruising, dark or 'tarry' stools, or coughing up blood. To avoid dizziness, try to stand up slowly from a sitting or lying position. If you have a history of stomach ulcers, speak to your doctor before taking aspirin.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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