Can I take Ashwagandha and Magnesium together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking ashwagandha and magnesium together is generally safe, but both substances can have a relaxing effect on the nervous system. This may lead to increased drowsiness or a very calm feeling in some people.
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Why this happens
Both ashwagandha and magnesium can influence GABA receptors in the brain, which are responsible for relaxation. While they work in different ways, their combined effect can be additive, meaning they may enhance each other's calming properties.
What you should do
It is usually fine to take these together. However, if you find yourself feeling overly sleepy or lethargic, try taking them at different times of the day (for example, ashwagandha in the morning and magnesium before bed) or reduce the dose of one. Always consult your GP before starting new supplements if you are taking prescribed medication for anxiety or sleep.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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