Can I take Reishi and White button together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known harmful interactions between reishi mushrooms and white button mushrooms. Both are edible fungi that are commonly consumed together in food or as part of a supplement routine.
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Why this happens
Reishi (Ganoderma lucidum) and white button mushrooms (Agaricus bisporus) do not interfere with each other's absorption or breakdown in the body. They have different biological profiles; reishi is primarily used for its potential immune-modulating properties, while white button mushrooms are a standard culinary food source.
What you should do
It is safe to consume these together. However, if you are taking reishi as a concentrated supplement, you should inform your doctor if you are also taking blood-thinning medications or blood pressure treatments, as reishi can sometimes have a mild additive effect on those specific types of medicines.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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