Can I take Aquipta and Naproxen together?

Why this happens

Aquipta and naproxen are processed by different pathways in the body. Aquipta is primarily broken down by liver enzymes (specifically CYP3A4), while naproxen is processed through different liver enzymes and cleared by the kidneys. They do not interfere with each other's absorption or effectiveness.

What you should do

You can take these medicines together as prescribed. Aquipta is typically used daily to prevent migraines, while naproxen is often used as a 'rescue' treatment to relieve pain during an attack. Always follow the dosage instructions provided by your doctor or pharmacist.

Important precautions

Asthma or aspirin sensitivity

Do not take naproxen if you have asthma or have ever had an allergic reaction to aspirin or other NSAIDs, as it can trigger a life-threatening breathing emergency (bronchospasm).

Stomach ulcers or bleeding

Naproxen significantly increases the risk of stomach ulcers and internal bleeding. Avoid it if you have a history of stomach issues, and stop taking it immediately if you notice black, tarry stools or vomit blood.

Severe kidney or liver disease

Aquipta is not recommended if you have severe liver disease or end-stage kidney disease, as your body may not be able to process the medicine safely.

Food and drink warnings

Alcohol

Drinking alcohol while taking naproxen can increase the risk of stomach irritation and serious side effects like stomach ulcers or bleeding. It is best to limit or avoid alcohol while taking this medicine.

Food (General)

You should take naproxen with or just after food. This helps to protect your stomach lining and reduces the risk of indigestion or stomach pain.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.