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Can I take Fluanxol and Pregabalin together?

Drug interaction guide

Taking Fluanxol (flupentixol) and pregabalin together can make you feel very sleepy, dizzy, and unsteady on your feet. It may also slow down your breathing and affect your coordination or concentration.

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Why this happens

Both medicines work by slowing down activity in the central nervous system (the brain and nerves). When used together, their sedative effects are added together (an additive effect), making the side effects much stronger than if you took either medicine alone.

What you should do

Use this combination with caution. Avoid driving, operating heavy machinery, or performing tasks that require you to be alert until you know how these medicines affect you. Do not drink alcohol while taking these medicines, as it will make the sleepiness much worse. If you feel extremely drowsy or have difficulty breathing, contact your doctor immediately.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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