Can I take Biotin and Vitamin D together?
Drug interaction guide
Originally published 24 Jan 2026
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There is no known harmful interaction between biotin (Vitamin B7) and Vitamin D. It is generally safe to take these two supplements together.
Why this happens
Biotin and Vitamin D are processed by the body using different pathways. Biotin is a water-soluble B vitamin, while Vitamin D is a fat-soluble vitamin. They do not compete for absorption in the gut, nor do they interfere with how the other is broken down or used by the body.
What you should do
You can continue to take both supplements as directed by your healthcare provider or the product packaging. However, be aware that high doses of biotin can interfere with certain laboratory blood tests (such as thyroid or heart enzyme tests). If you are having blood work done, inform your doctor or the lab technician that you are taking a biotin supplement.
Important precautions
Blood tests
Biotin can significantly interfere with laboratory blood tests, including thyroid function and heart attack markers (troponin), leading to dangerously incorrect results. You must stop taking biotin at least 48 hours before having any blood tests and inform your doctor.
Food and drink warnings
High-fat meals
Vitamin D is a fat-soluble vitamin. It is absorbed much more effectively when taken with a meal that contains some fat (such as eggs, avocado, nuts, or dairy). Taking it on an empty stomach may reduce its effectiveness.
Raw egg whites
Consuming large amounts of raw egg whites over a long period can prevent your body from absorbing biotin. This is because raw egg whites contain a protein called avidin that binds to biotin. Cooked eggs do not cause this issue.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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