Can I take Aspirin and Danazol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking aspirin and danazol together can increase your risk of bleeding, particularly in the stomach or gut. It may also increase the risk of bruising or bleeding from the gums.
In this article:
Continue reading below
Why this happens
Danazol can sometimes lower the number of platelets in your blood (the cells that help blood clot). Aspirin also prevents blood from clotting by making platelets less 'sticky'. When used together, these two effects combine to make it much harder for your body to stop any bleeding.
What you should do
Back to contentsUse this combination with caution. If you are taking aspirin for pain relief, consider using paracetamol instead. If you have been prescribed aspirin by a doctor (for example, for heart health), speak to them before starting danazol. Seek medical advice immediately if you notice unusual bruising, black tarry stools, or persistent bleeding.
Continue reading below
Important precautions
Back to contentsAsthma
Do not take aspirin if you have a history of asthma or wheezing triggered by aspirin or other anti-inflammatory painkillers, as it can cause a life-threatening asthma attack.
Pregnancy
You must use effective non-hormonal contraception (such as condoms) while taking danazol. It can cause the development of male characteristics in a female foetus if taken during pregnancy.
Children under 16 years old
Never give aspirin to children or teenagers under 16 unless specifically prescribed by a doctor. It can cause Reye’s syndrome, a rare but fatal condition affecting the brain and liver.
Food and drink warnings
Back to contentsAlcohol
Drinking alcohol while taking aspirin increases the risk of irritation and bleeding in your stomach and intestines. It is best to limit or avoid alcohol, especially if you take aspirin regularly.
Caffeine
Aspirin is often combined with caffeine in over-the-counter painkillers. However, consuming high amounts of additional caffeine (from coffee, tea, or energy drinks) can increase the risk of stomach upset and may lead to jitteriness or a rapid heartbeat.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Atorvastatin and Prednisolone together?
Taking atorvastatin and prednisolone together may increase the risk of muscle-related side effects, such as muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis, where muscle tissue breaks down and can cause kidney damage. Additionally, prednisolone can raise blood sugar levels, which may slightly reduce the effectiveness of atorvastatin in managing your cholesterol profile.

Treatment and medication
Can I take Lansoprazole and Quetiapine together?
Taking lansoprazole and quetiapine together is generally safe, but lansoprazole might slightly change how much quetiapine your body absorbs. This could potentially make the quetiapine slightly less effective for some people. Additionally, both medications can occasionally cause drowsiness or dizziness, which might be more noticeable when taken together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.