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Can I take Lactulose and Paracetamol together?

Drug interaction guide

There are no known interactions between lactulose and paracetamol. It is safe to take these two medicines together.

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Why this happens

Lactulose is a sugar-based laxative that works locally in the bowel and is not absorbed into the bloodstream. Paracetamol is absorbed in the small intestine and processed by the liver. Because they work in different parts of the body and are handled by different systems, they do not interfere with each other.

What you should do

You can take both medicines as prescribed or according to the packet instructions. Ensure you drink plenty of water while taking lactulose to help it work effectively.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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