Can I take Aspirin and Dalteparin together?

Why this happens

Both medicines work to prevent blood clots but in different ways. Aspirin makes 'platelets' (tiny blood cells) less sticky, while dalteparin (a 'blood thinner' or anticoagulant) interferes with the proteins that help blood clot. When used together, your blood becomes much thinner than it would be with either medicine alone, making it very difficult for your body to stop any bleeding.

You should only take these two medicines together if specifically instructed to do so by a specialist doctor (such as a cardiologist or haematologist). If you are prescribed both, watch closely for signs of bleeding, such as dark 'tarry' stools, coughing up blood, or severe bruising. Seek medical advice immediately if you have a fall or a head injury. Do not take over-the-counter aspirin or similar painkillers like ibuprofen while using dalteparin.

Asthma

Do not take aspirin if you have a history of asthma or wheezing triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a severe, life-threatening asthma attack.

Active bleeding or stomach ulcers

Both medicines significantly increase your risk of severe bleeding. Do not take them if you have an active stomach ulcer or any condition causing active bleeding. Seek immediate medical help if you notice signs of internal bleeding, such as black, tarry stools or vomiting blood.

Spinal or epidural anaesthesia

If you require a spinal injection or epidural, you must inform the doctor you are using dalteparin. There is a risk of a blood clot forming in the spine (spinal haematoma), which can cause permanent paralysis.

Alcohol

Drinking alcohol while taking aspirin can increase the risk of stomach irritation and bleeding. It is best to limit alcohol intake or avoid it altogether, especially if you are taking aspirin regularly.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.