Skip to main content

Can I take Atorvastatin and Codeine bp together?

Drug interaction guide

There is no known direct interaction between atorvastatin and codeine. It is generally safe to take these two medications together.

Video picks for Drug interactions

Continue reading below

Why this happens

Atorvastatin and codeine are processed by different pathways in the liver. Atorvastatin is primarily broken down by an enzyme called CYP3A4, while codeine is mainly processed by CYP2D6. Because they do not compete for the same 'machinery' in the body, they do not interfere with each other's levels.

You can take these medicines together as prescribed. However, always be mindful of general side effects. Codeine can cause drowsiness and constipation, while statins can occasionally cause muscle aches. If you experience unusual muscle pain or extreme tiredness, consult your doctor.

Continue reading below

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.