Can I take Atorvastatin and Losartan together?

Why this happens

Atorvastatin and losartan are processed by different pathways in the liver and do not interfere with how the body absorbs or removes each other. They also work on different systems (cholesterol vs. blood pressure) without causing harmful additive effects.

You can safely take these medicines together as prescribed by your doctor. It is usually best to take them at the same time each day to help you remember. Always inform your doctor if you experience unusual muscle pain or weakness, which is a rare side effect of statins, but this is not caused by taking losartan.

Pregnancy

You must not take these medicines if you are pregnant or planning to become pregnant, as they can cause serious harm to an unborn baby. Use effective contraception while taking these medicines.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Alcohol

While there is no direct 'chemical' interaction, both medicines can affect the liver or lower blood pressure. Drinking alcohol while taking losartan can increase the medicine's blood-pressure-lowering effect, making you feel dizzy or lightheaded. For atorvastatin, heavy drinking increases the risk of liver problems. It is advised to keep within the recommended weekly limits.

Salt substitutes (Potassium-rich)

Losartan can increase the levels of potassium in your blood. Many 'low-sodium' salt substitutes use potassium chloride instead of sodium. Using these while taking losartan can lead to dangerously high potassium levels (hyperkalaemia). Check labels on salt substitutes and consult your pharmacist.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.