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Can I take Avodart soft and Brintellix together?

Drug interaction guide

There are no known significant interactions between Avodart (dutasteride) and Brintellix (vortioxetine). It is generally considered safe to take these two medications together.

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Why this happens

These drugs are processed by different pathways in the liver. Avodart is primarily broken down by the CYP3A4 enzyme, while Brintellix is mainly processed by CYP2D6. Because they use different 'routes' for metabolism, they do not interfere with each other's levels in the bloodstream. Additionally, they work on completely different systems in the body (hormones vs. brain chemicals), so their effects do not overlap.

You can take these medications together as prescribed by your doctor. As with any new medication, monitor how you feel and report any unusual side effects to your healthcare provider.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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