Can I take Azathioprine and Lansoprazole together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Lansoprazole may slightly reduce the amount of azathioprine that your body absorbs. This could potentially make the azathioprine slightly less effective at controlling your condition.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Azathioprine needs a certain level of stomach acid to dissolve and be absorbed properly. Lansoprazole works by reducing stomach acid, which can change how well azathioprine enters your bloodstream.
What you should do
Back to contentsIt is generally safe to take these together, but you should monitor your condition closely. If you feel your symptoms are returning or worsening, speak to your doctor. They may suggest taking the two medicines at different times of the day.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Ashwagandha and Vitamin d2 together?
There are no known significant interactions between ashwagandha and vitamin D2 (ergocalciferol). It is generally considered safe to take these two supplements together.

Treatment and medication
Can I take Acetaminophen and Levocetirizine together?
Taking paracetamol (acetaminophen) and levocetirizine together is generally considered safe. There are no known major interactions between these two medicines. However, both can occasionally cause drowsiness or tiredness in some people. If you experience these side effects, they may be slightly more noticeable when taking both medicines at the same time.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.