Can I take Bisoprolol and Losartin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking bisoprolol and losartan together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It can also lead to increased levels of potassium in your blood.
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Why this happens
Both medicines work to lower blood pressure but in different ways. Bisoprolol is a beta-blocker that slows the heart rate, while losartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels. When used together, their effects add up (additive effect). Additionally, both can affect how your kidneys handle potassium.
What you should do
It is very common for doctors to prescribe these two medicines together, but you should be monitored closely. Your doctor will likely perform regular blood tests to check your kidney function and potassium levels. To avoid dizziness, try to get up slowly from a sitting or lying position. If you feel very dizzy, have a racing heart, or feel unusually tired, contact your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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