Can I take Candesartan and Nortriptyline together?

Why this happens

Candesartan is a blood pressure medicine that relaxes your blood vessels. Nortriptyline, while used for mood or pain, can also lower blood pressure as a side effect. When used together, these effects add up, increasing the risk of low blood pressure (hypotension).

You can take these together, but be careful when moving from a sitting or lying position to standing. Rise slowly to give your body time to adjust. If you feel very dizzy, sit or lie down immediately. Monitor your blood pressure at home if possible and tell your doctor if you feel constantly lightheaded or faint.

Pregnancy

You must not take candesartan if you are pregnant. It can cause serious harm or death to an unborn baby, especially if used during the second and third trimesters. Use effective contraception while taking it.

Heart conditions (e.g. recent heart attack or arrhythmia)

Nortriptyline must be avoided if you have recently had a heart attack or have certain heart rhythm disorders, as it can significantly affect your heart rate and electrical activity.

Alcohol

Alcohol can increase the blood-pressure-lowering effect of candesartan and the sedative effect of nortriptyline. This may make you feel dizzy, lightheaded, or very sleepy. It is best to limit alcohol intake, especially when starting these medicines.

Potassium-rich foods (e.g., bananas, spinach, salt substitutes)

Candesartan can increase the levels of potassium in your blood. Consuming large amounts of foods very high in potassium or using potassium-based salt substitutes (such as Lo-Salt) can lead to dangerously high potassium levels (hyperkalaemia). You should avoid using potassium-based salt substitutes unless advised otherwise by your doctor.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.