Can I take Co-codamol and Omeprazole together?

Why this happens

These two medications are processed by different pathways in the body. Omeprazole works on the acid-producing pumps in the stomach, while co-codamol (a mix of paracetamol and codeine) works on pain receptors and the central nervous system. They do not significantly interfere with each other's absorption or metabolism.

What you should do

It is safe to take these two medications together. If you find that the codeine in the co-codamol causes constipation, ensure you drink plenty of water and eat high-fibre foods. If you have any concerns about your stomach health or persistent pain, speak with your pharmacist or GP.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.