Can I take Co-dydramol and Naproxen together?

Why this happens

Co-dydramol contains two ingredients: paracetamol and dihydrocodeine. Naproxen is a non-steroidal anti-inflammatory drug (NSAID). While paracetamol and naproxen are often used together safely, the combination of an NSAID (naproxen) and an opioid (dihydrocodeine) can increase the strain on your gastrointestinal tract. Furthermore, taking multiple painkillers increases the workload on your kidneys to clear the medication from your body.

This combination is generally considered safe for short-term use if prescribed by a healthcare professional, but you should use caution. Always take naproxen with food to protect your stomach. Do not exceed the recommended dose of either medication. If you notice any dark, tarry stools, severe stomach pain, or persistent indigestion, stop taking the medication and contact your doctor immediately. Ensure you stay well-hydrated to support your kidney function.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.