Can I take Colicure and Temo together?

Why this happens

Colicure (activated dimeticone) works physically in the gut to help small bubbles of gas join together, making them easier to pass. Temo (temozolomide) is a cytotoxic medicine that works by damaging the DNA of cancer cells. Because they work through entirely different pathways and dimeticone is not absorbed into the bloodstream, they do not interfere with each other's chemical processes.

You can safely take these medicines together. If you are taking Temo, it is important to follow your oncology team's advice regarding anti-sickness medication. If your digestive symptoms (like bloating or constipation) worsen while taking these together, please inform your specialist nurse or doctor, as they may want to adjust your supportive care plan.

Pregnancy and Contraception

This medicine can cause severe birth defects. Both men and women must use highly effective contraception during treatment. Men should not father a child for at least 3 months after the final dose.

Pneumocystis jirovecii pneumonia (PCP) risk

When taken with radiotherapy, you are at higher risk of a severe lung infection (PCP). Your doctor must prescribe additional medicine to prevent this.

Food (General)

To reduce the risk of nausea and vomiting, you should take this medicine on an empty stomach (at least one hour before a meal). Taking it with food can also reduce how much of the medicine is absorbed by your body.

Alcohol

While there is no direct interaction, alcohol can worsen side effects like nausea and dizziness. It may also increase the risk of liver irritation when combined with chemotherapy. It is best to limit or avoid alcohol during treatment.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.