Can I take Dapagliflozin and Gliclazide together?

Why this happens

Dapagliflozin works by helping your kidneys remove excess sugar through your urine. Gliclazide works by stimulating your pancreas to produce more insulin. When used together, the 'additive effect' of both drugs lowering your blood sugar simultaneously makes a low blood sugar episode more likely.

You should monitor your blood sugar levels more frequently when starting this combination or when your dose is changed. Make sure you know how to recognise the signs of a 'hypo' (such as sweating, shaking, hunger, or irritability) and always carry a fast-acting glucose source (like glucose tablets or sugary sweets). Your doctor may need to reduce your dose of gliclazide to prevent your blood sugar from dropping too low.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.