Can I take Diclofenac and Side effects together?

Why this happens

Diclofenac works by blocking enzymes (COX-1 and COX-2) that produce chemicals called prostaglandins. While this reduces pain and inflammation, these same prostaglandins are needed to protect the stomach lining and maintain healthy blood flow to the kidneys.

Always take diclofenac with food to protect your stomach. Use the lowest dose for the shortest time possible. Seek medical help immediately if you notice black, tarry stools, severe stomach pain, or swelling in your ankles. Avoid taking it if you have a history of stomach ulcers or heart disease unless specifically told to by your doctor.

Asthma

Do not take this medicine if you have ever had an asthma attack, wheezing, or a severe allergic reaction triggered by aspirin or other NSAIDs. It can cause a life-threatening narrowing of the airways.

Heart and Circulatory Disease

Diclofenac carries a higher risk of heart attack and stroke than other similar painkillers. You must not take it if you have established heart disease, peripheral arterial disease, or have previously had a stroke.

Stomach Ulcers and Bleeding

This medicine can cause serious stomach bleeding or ulcers without warning. The risk is significantly higher if you are over 65, have a history of ulcers, or are taking blood-thinning medications like warfarin.

Alcohol

Drinking alcohol while taking diclofenac can increase the risk of stomach irritation and bleeding. It is best to limit or avoid alcohol, especially if you are taking this medicine long-term.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.