Can I take Ecosprin av75 and Pulmoclear together?
Drug interaction guide
Originally published 14 Mar 2026
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There is a moderate risk of stomach irritation or bleeding when taking these medicines together. Ecosprin AV 75 contains aspirin, which can thin the blood and irritate the stomach lining. Pulmoclear contains acebrophylline, which can also cause stomach upset or increase the risk of acidity. Taking them together may increase the chance of developing stomach pain, indigestion, or in rare cases, a stomach ulcer.
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Why this happens
Both aspirin (in Ecosprin AV) and acebrophylline (in Pulmoclear) can affect the protective lining of the stomach. Aspirin inhibits prostaglandins that protect the stomach, while acebrophylline can increase gastric acid secretion and cause gastrointestinal irritation. This creates an additive effect on the digestive system.
What you should do
Back to contentsYou can take these medicines together, but you should take them after food to protect your stomach. If you have a history of stomach ulcers or acid reflux, speak to your doctor before starting Pulmoclear. Seek medical advice immediately if you notice signs of stomach bleeding, such as very dark/tarry stools or vomiting blood (which may look like coffee grounds).
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Important precautions
Back to contentsPregnancy
You must not take this medicine if you are pregnant or planning to conceive. The statin component can cause serious harm to an unborn baby, and aspirin increases the risk of bleeding during pregnancy. Use effective contraception while taking it.
Active bleeding or stomach ulcers
Do not take this medicine if you have an active stomach ulcer or a history of bleeding in the brain, as the aspirin component significantly increases the risk of life-threatening haemorrhage.
Unexplained muscle pain
Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately. In rare cases, the statin component can cause severe muscle breakdown (rhabdomyolysis) which can lead to kidney damage.
Food and drink warnings
Back to contentsCaffeine (Coffee, Tea, Energy drinks)
Acebrophylline is related to theophylline. Consuming high amounts of caffeine can increase the risk of side effects such as nausea, palpitations, nervousness, or tremors, as both substances stimulate the central nervous system.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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