Can I take Entresto and Furosemide together?

Why this happens

Both medicines work to remove excess fluid and salt from your body and lower your blood pressure. Entresto contains sacubitril, which increases the effect of natural chemicals that make you pass more urine, while furosemide is a 'water pill' (diuretic) that does the same. When used together, their effects add up, which can lead to dehydration or a sudden drop in blood pressure.

You can take these medicines together, but your doctor should monitor you closely. Your doctor may need to adjust your dose of furosemide when you start Entresto. Watch out for signs of low blood pressure, such as feeling dizzy, lightheaded, or faint, especially when standing up. Ensure you attend any scheduled blood tests to check your kidney function.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.