Can I take Evening primrose oil and Turmeric with black pepper together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking evening primrose oil and turmeric together may increase your risk of bruising or bleeding. This is because both supplements have properties that can thin the blood or slow down the formation of blood clots.
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Why this happens
Evening primrose oil contains gamma-linolenic acid (GLA), which can interfere with how platelets (the cells that help blood clot) stick together. Turmeric (curcumin) also has natural anti-clotting effects. When used together, these effects can add up, making it harder for your blood to clot if you injure yourself. Additionally, the black pepper (piperine) in your supplement can increase the absorption of many substances, potentially making the effects of the evening primrose oil stronger.
What you should do
Use this combination with caution. If you notice unusual bruising, nosebleeds, or bleeding gums, stop taking them and speak to your doctor. You should stop taking both supplements at least two weeks before any scheduled surgery. If you are already taking prescribed blood thinners (like warfarin, aspirin, or clopidogrel), do not take this combination without medical supervision.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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