Can I take Evening primrose oil and Vitamin b complex together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known significant interactions between evening primrose oil and vitamin B complex supplements. They are generally considered safe to take together.
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Why this happens
Evening primrose oil is a source of essential fatty acids (specifically gamma-linolenic acid), while vitamin B complex consists of water-soluble vitamins. These substances are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.
What you should do
You can safely take these two supplements together. As with all supplements, it is best to follow the dosage instructions on the packaging or those provided by your healthcare professional. Taking them with food may help prevent any mild stomach upset.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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