Can I take Evening primrose oil and Vitamin B complex together?

Why this happens

Evening primrose oil is a source of essential fatty acids (specifically gamma-linolenic acid), while vitamin B complex consists of water-soluble vitamins. These substances are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.

What you should do

You can safely take these two supplements together. As with all supplements, it is best to follow the dosage instructions on the packaging or those provided by your healthcare professional. Taking them with food may help prevent any mild stomach upset.

Important precautions

Epilepsy or Schizophrenia

Evening primrose oil may increase the risk of seizures, particularly in people with a history of epilepsy or those taking phenothiazine medications for schizophrenia.

Bleeding disorders or upcoming surgery

Evening primrose oil can thin the blood and increase the risk of bruising or bleeding. You must stop taking it at least two weeks before any scheduled surgery.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol when taking evening primrose oil. While there is no direct chemical interaction, both substances can lower the seizure threshold in susceptible individuals, and alcohol may worsen the side effects of the supplement, such as nausea or indigestion.

It is best to avoid or strictly limit alcohol when taking Vitamin B complex. Alcohol interferes with the absorption of B vitamins (especially B1 and B12) and increases their excretion from the body, making the supplement less effective. Additionally, chronic alcohol use can lead to severe B vitamin deficiencies.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.