Can I take Ezetimibe and Rosuvastatin together?

Why this happens

Both medicines work in different ways to lower cholesterol: rosuvastatin reduces the amount of cholesterol your liver produces, while ezetimibe reduces the amount of cholesterol your body absorbs from food. Because both drugs can independently affect muscle tissue, using them together can have an 'additive' effect, meaning the small risk of muscle damage from each drug is combined.

You can usually take these medicines together safely, but you should be aware of your body's reactions. If you experience any unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or feel generally unwell—contact your doctor immediately. Your doctor may want to perform a blood test to check your muscle enzymes (CK levels) before starting the combination or if you develop symptoms.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.