Can I take Fluvoxamine and Intuniv together?

Why this happens

Fluvoxamine blocks a specific enzyme in the liver (called CYP3A4) that is responsible for breaking down guanfacine. Because the liver cannot clear the guanfacine as quickly as usual, the medicine builds up to higher levels in your body.

You must speak to your doctor before taking these two medicines together. If they are prescribed together, your doctor will likely need to reduce your dose of Intuniv (often by half) and monitor your blood pressure and heart rate closely. Seek medical help immediately if you feel very dizzy, confused, or like you might pass out.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.