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Can I take Furosemide and Losartan together?

Drug interaction guide

Taking these two medicines together can cause your blood pressure to drop too low (hypotension). This might make you feel dizzy, lightheaded, or faint, especially when you stand up quickly. It can also put extra strain on your kidneys, potentially leading to reduced kidney function or dehydration.

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Why this happens

Both medicines work to lower blood pressure but in different ways. Furosemide is a 'water tablet' (diuretic) that removes excess fluid and salt from your body. Losartan blocks a hormone that narrows blood vessels. When used together, the fluid loss from furosemide can make the blood pressure-lowering effect of losartan much stronger. This combination can also reduce the blood flow to the kidneys.

You can take these together, but your doctor should monitor you closely, especially when starting the treatment or changing the dose. To stay safe:

  1. Stay well-hydrated unless your doctor has given you a fluid limit.

  2. Get up slowly from a sitting or lying position to avoid dizziness.

  3. Your doctor will likely perform regular blood tests to check your kidney function and salt levels (like potassium).

  4. Contact your doctor if you feel very dizzy, stop passing urine, or have severe muscle weakness.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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