Can I take Furosemide and Strivit D3 together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking furosemide and Strivit D3 (Vitamin D3) together can lead to high levels of calcium in your blood. This can cause symptoms like feeling sick, constipation, or feeling very thirsty.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Furosemide is a 'water tablet' that changes how your kidneys handle minerals. Vitamin D3 helps your body absorb calcium. When used together, they can sometimes cause calcium to build up in the bloodstream rather than being excreted.
What you should do
Back to contentsYou can usually take these together, but your doctor may want to monitor your calcium levels with occasional blood tests. If you start feeling unusually tired, thirsty, or nauseous, let your doctor know.
Continue reading below
Important precautions
Back to contentsDehydration and low blood pressure
Furosemide is a potent diuretic. You must not take it if you are already severely dehydrated or cannot pass urine. It can cause a rapid drop in blood pressure and salt levels, especially if you are also taking other blood pressure medicines.
Gout
Furosemide can increase the levels of uric acid in your blood, which may trigger a painful gout attack or make existing gout worse.
Sulphonamide Allergy
If you have a known allergy to sulphonamide antibiotics (such as sulfamethoxazole), you may also be allergic to furosemide. You must inform your healthcare provider before taking this medicine.
High calcium levels (Hypercalcaemia)
Do not take Strivit D3 if you have high calcium levels in your blood or urine, or certain types of kidney stones, as Vitamin D3 increases calcium absorption and can lead to kidney damage.
Food and drink warnings
Back to contentsAlcohol
It is best to avoid or strictly limit alcohol while taking furosemide. Alcohol can increase the blood-pressure-lowering effect of this medicine, which may make you feel dizzy, light-headed, or faint, especially when standing up. Both alcohol and furosemide are diuretics, which increases the risk of dehydration.
Liquorice (Natural) / Liquorice Root
Avoid eating large amounts of natural liquorice or taking liquorice root supplements. Natural liquorice can cause the body to lose potassium and retain salt, which opposes the action of furosemide and can lead to dangerously low potassium levels.
Caffeine (Coffee, Tea, Energy Drinks)
Limit your intake of caffeine. Caffeine is a mild diuretic and can increase the water-loss effect of furosemide, potentially increasing the risk of dehydration or electrolyte imbalances.
High-fat meals
Vitamin D3 is fat-soluble. Taking your Strivit D3 tablet with your largest meal of the day (or a meal containing some fat) helps your body absorb the medicine more effectively.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Atorvastatin and Spironolactone together?
Taking these two medicines together can occasionally lead to a build-up of potassium in your blood (hyperkalaemia). While both drugs are often prescribed together safely, they can both influence how your body handles minerals and muscle health. There is also a very small increased risk of muscle-related side effects.

Treatment and medication
Can I take Atorvastatin and Turkey tail together?
There is no evidence of a direct harmful interaction between atorvastatin and turkey tail mushroom (Trametes versicolor). However, turkey tail may have a mild effect on how the liver processes certain medications, and it may also have its own subtle cholesterol-lowering properties.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.