Can I take Furosemide and Strivit D3 together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking furosemide and Strivit D3 (Vitamin D3) together can lead to high levels of calcium in your blood. This can cause symptoms like feeling sick, constipation, or feeling very thirsty.
Why this happens
Furosemide is a 'water tablet' that changes how your kidneys handle minerals. Vitamin D3 helps your body absorb calcium. When used together, they can sometimes cause calcium to build up in the bloodstream rather than being excreted.
What you should do
You can usually take these together, but your doctor may want to monitor your calcium levels with occasional blood tests. If you start feeling unusually tired, thirsty, or nauseous, let your doctor know.
Important precautions
Dehydration and low blood pressure
Furosemide is a potent diuretic. You must not take it if you are already severely dehydrated or cannot pass urine. It can cause a rapid drop in blood pressure and salt levels, especially if you are also taking other blood pressure medicines.
Gout
Furosemide can increase the levels of uric acid in your blood, which may trigger a painful gout attack or make existing gout worse.
Sulphonamide Allergy
If you have a known allergy to sulphonamide antibiotics (such as sulfamethoxazole), you may also be allergic to furosemide. You must inform your healthcare provider before taking this medicine.
High calcium levels (Hypercalcaemia)
Do not take Strivit D3 if you have high calcium levels in your blood or urine, or certain types of kidney stones, as Vitamin D3 increases calcium absorption and can lead to kidney damage.
Food and drink warnings
Alcohol
It is best to avoid or strictly limit alcohol while taking furosemide. Alcohol can increase the blood-pressure-lowering effect of this medicine, which may make you feel dizzy, light-headed, or faint, especially when standing up. Both alcohol and furosemide are diuretics, which increases the risk of dehydration.
Liquorice (Natural) / Liquorice Root
Avoid eating large amounts of natural liquorice or taking liquorice root supplements. Natural liquorice can cause the body to lose potassium and retain salt, which opposes the action of furosemide and can lead to dangerously low potassium levels.
Caffeine (Coffee, Tea, Energy Drinks)
Limit your intake of caffeine. Caffeine is a mild diuretic and can increase the water-loss effect of furosemide, potentially increasing the risk of dehydration or electrolyte imbalances.
High-fat meals
Vitamin D3 is fat-soluble. Taking your Strivit D3 tablet with your largest meal of the day (or a meal containing some fat) helps your body absorb the medicine more effectively.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
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