Can I take Gabapentin and Naproxen together?

Why this happens

Naproxen appears to increase the absorption of gabapentin in the gut by approximately 12% to 15%. Furthermore, both drugs are cleared from the body through the kidneys; naproxen can sometimes reduce kidney function, which may slow down how quickly gabapentin is removed from your system.

What you should do

It is generally safe to take these together, but you should be aware that you might feel more sleepy or dizzy than usual. Start with the lowest effective dose of naproxen and monitor how you feel. If you experience significant drowsiness, confusion, or swelling in your legs, contact your doctor. Ensure you stay well-hydrated to help your kidneys process the medications.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.