Skip to main content

Can I take Hydroxocobalamin and Stexerol D3 together?

Drug interaction guide

There are no known harmful interactions between hydroxocobalamin and Stexerol-D3. It is safe to take these two medications together.

Video picks for Drug interactions

Continue reading below

Why this happens

Hydroxocobalamin is a form of Vitamin B12, and Stexerol-D3 is a brand of Vitamin D3 (cholecalciferol). These vitamins are processed by different pathways in the body and do not interfere with each other's absorption, metabolism, or effectiveness.

You can continue to take both medications as prescribed by your doctor. They are often prescribed together to treat different vitamin deficiencies.

Continue reading below

Hypokalaemia (low potassium)

When starting treatment for severe vitamin B12 deficiency, your potassium levels can drop rapidly as your body produces new red blood cells. This can be dangerous for your heart and may require monitoring by your doctor.

Hypercalcaemia (high calcium) or kidney stones

Do not take Stexerol D3 if you have high levels of calcium in your blood or urine, or a history of kidney stones, as vitamin D3 increases calcium absorption and can worsen these conditions.

Alcohol

It is best to avoid or strictly limit alcohol while receiving hydroxocobalamin treatment. Excessive alcohol consumption can interfere with the absorption of Vitamin B12 and may worsen the underlying deficiency being treated. Combining alcohol with medication also increases the risk of liver strain.

It is best to avoid or strictly limit alcohol while taking Stexerol D3. Long-term heavy alcohol use can interfere with how your body processes Vitamin D and may weaken your bones.

Continue reading below

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.