Can I take % intravenous infusion - carelide and Midodrine together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Combining these two treatments can lead to a significant and potentially dangerous increase in blood pressure (hypertension). This is particularly risky when lying down.
In this article:
Continue reading below
Why this happens
Both substances work to increase blood pressure but in different ways. Midodrine constricts blood vessels, while intravenous fluids (like Carelide) increase the volume of fluid in your circulation. Together, they can cause the blood pressure to rise much higher than intended.
What you should do
Back to contentsThis combination should only be used under strict medical supervision, usually in a hospital setting. Your blood pressure must be monitored frequently. If you are at home and have been prescribed both, contact your doctor immediately. Avoid taking midodrine just before lying down for long periods.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Allerwel am and Calpol together?
There are no known harmful interactions between Allerwel AM and Calpol. It is generally safe to take these two medicines together as long as you follow the recommended doses for each.

Treatment and medication
Can I take Amitriptyline and Co-codamol together?
Taking these two medicines together can make you feel very sleepy, dizzy, and confused. It can also increase the risk of breathing difficulties and severe constipation.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.