Can I take Lercanidipine and Levothyrixine together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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There is no direct interaction between lercanidipine and levothyroxine. However, if you are taking lercanidipine to treat high blood pressure caused by an overactive or underactive thyroid, your doctor may need to adjust your doses as your thyroid levels stabilise.
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Why this happens
Lercanidipine is a calcium channel blocker used for high blood pressure, and levothyroxine is a hormone replacement for the thyroid. They are processed by different pathways in the body and do not interfere with each other's absorption or metabolism.
What you should do
Back to contentsYou can safely take these two medicines together. It is best to take levothyroxine on an empty stomach, at least 30 to 60 minutes before breakfast. Lercanidipine should also be taken at least 15 minutes before a meal. Continue to have your regular blood tests to monitor your thyroid levels and blood pressure.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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