Can I take Lercanidipine and Pregabalin together?

Why this happens

Lercanidipine works by relaxing blood vessels, which can sometimes cause fluid to leak into the tissues (swelling). Pregabalin affects the central nervous system and can also cause fluid retention and drowsiness. When used together, their similar side-effect profiles can have an additive effect on your body.

What you should do

It is generally safe to take these together, but you should be aware of increased side effects. To stay safe, get up slowly from a sitting or lying position to avoid dizziness. If you notice significant swelling in your ankles, or if the drowsiness interferes with your daily activities (like driving), speak to your GP. Do not stop taking either medication without medical advice.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.