Can I take Levothyroxine and Pinefeld together?

Why this happens

Levothyroxine is a thyroid hormone, and Pinefeld (felodipine) is a calcium channel blocker used for high blood pressure. Thyroid hormones affect your metabolism. If you are hyperthyroid (too much hormone) or hypothyroid (too little), your body may break down felodipine faster or slower than usual, which could make the blood pressure medicine more or less effective.

What you should do

You can take these medicines together. However, if your doctor changes your levothyroxine dose, you should monitor your blood pressure more closely. If you feel dizzy, get a headache, or notice your heart racing, contact your doctor. Always leave a gap of at least 30 to 60 minutes between taking your levothyroxine (usually on an empty stomach) and any other medications or food.

Important precautions

Heart disease (e.g. angina, heart failure)

Levothyroxine increases the workload on your heart. If you experience chest pain, palpitations, or shortness of breath, you must contact your doctor immediately as your dose may need adjusting.

Grapefruit consumption

Do not drink grapefruit juice or eat grapefruit while taking this medicine. It can significantly increase the amount of medicine in your blood, leading to a dangerous drop in blood pressure.

Food and drink warnings

Dairy products (Milk, Yoghurt, Cheese)

Calcium found in dairy products can significantly reduce the amount of levothyroxine your body absorbs. You should avoid eating or drinking dairy products within 4 hours of taking your dose.

Caffeine (Coffee and Tea)

Coffee and tea can interfere with how levothyroxine is absorbed. You should wait at least 30 to 60 minutes after taking your medicine before drinking coffee or tea.

Soya products

Soya can stop levothyroxine from being absorbed properly. If you eat a lot of soya, your doctor may need to monitor your thyroid levels more closely.

Papaya

Some studies suggest that eating papaya may reduce the absorption of levothyroxine. It is best to keep your intake of papaya consistent or avoid it around the time you take your medication.

Grapefruit and Grapefruit juice

Grapefruit can increase the level of this medicine in your blood, which may increase the risk of side effects like dizziness, headaches, or a rapid heartbeat. Avoid grapefruit products while taking this medicine.

Alcohol

Drinking alcohol while taking Pinefeld can cause your blood pressure to drop too low, making you feel dizzy, lightheaded, or faint. It is best to limit or avoid alcohol.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.