Can I take Losartan and Paracetamol together?

Why this happens

Losartan is a blood pressure medication (angiotensin II receptor blocker) and paracetamol is a painkiller. They are processed by different pathways in the body and do not interfere with how the other works. Unlike some other painkillers (such as ibuprofen), paracetamol does not typically affect blood pressure or kidney function when taken at normal doses.

What you should do

You can take paracetamol while you are on losartan. Always stick to the recommended dose of paracetamol (usually no more than eight 500mg tablets in 24 hours). If you find you need to take paracetamol every day for a long time, it is a good idea to mention this to your doctor or pharmacist so they can monitor your blood pressure.

Important precautions

Pregnancy

You must not take this medicine if you are pregnant or planning to become pregnant, as it can cause serious harm or death to an unborn baby.

High potassium levels (Hyperkalaemia)

Avoid using salt substitutes containing potassium or taking potassium supplements, as this medicine can cause your potassium levels to become dangerously high.

Liver damage (Overdose risk)

Never take more than the recommended dose, and do not take this with any other products containing paracetamol (such as cold and flu remedies), as even a small overdose can cause fatal liver damage.

Food and drink warnings

Alcohol

Drinking alcohol while taking losartan can increase the blood pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.

Potassium-rich foods and salt substitutes

Losartan can increase the levels of potassium in your blood. You should avoid using salt substitutes that contain potassium (often labelled as 'low sodium' salts) and avoid consuming excessive amounts of potassium-rich foods (such as bananas, spinach, or sweet potatoes) without consulting your doctor, as high potassium levels can affect your heart rhythm.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.