Can I take Mirtazapine and Zentiva clopidogrel together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking mirtazapine and clopidogrel together may increase your risk of bleeding. This includes bruising more easily, nosebleeds, or more serious bleeding inside the body.
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Why this happens
Mirtazapine can affect how platelets (the cells that help your blood clot) work. Clopidogrel is a 'blood thinner' specifically designed to stop platelets from sticking together. When used together, their effects on platelets can add up, making it harder for your blood to clot if you are injured or have an internal bleed.
What you should do
You can take these medicines together, but you should be aware of the increased bleeding risk. Watch out for signs of unusual bleeding, such as dark or tarry stools, coughing up blood, blood in your urine, or large bruises that appear for no reason. If you notice any of these, or if you have a cut that will not stop bleeding, contact your doctor immediately. Do not stop taking either medication without speaking to your doctor first.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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