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Can I take Pregabalin and Ripinrole together?

Drug interaction guide

Taking pregabalin and ropinirole together can increase the risk of side effects like extreme sleepiness, dizziness, and confusion. You may feel more 'spaced out' or unsteady on your feet than usual.

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Why this happens

Both medicines act on the central nervous system (the brain) to slow down certain signals. When used together, their sedative effects add up, making the overall impact on your alertness much stronger.

What you should do

Be very careful when starting this combination or changing your dose. Do not drive, cycle, or operate machinery until you know how these medicines affect you together. Avoid alcohol, as it will make the drowsiness even worse. If you feel excessively sleepy or struggle to stay awake during the day, speak to your doctor.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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