Can I take Probiotics and Vitamin d together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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There is no evidence that probiotics and vitamin D interfere with each other. In fact, they are often taken together because they may work in harmony to support your immune system and gut health. Some studies even suggest that certain probiotics might help your body absorb vitamin D more effectively.
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Why this happens
Probiotics (beneficial bacteria) and vitamin D (a fat-soluble vitamin) use different pathways in the body. Probiotics live in the gut and influence the microbiome, while vitamin D is absorbed into the bloodstream. There is no competition for absorption or metabolism between the two.
What you should do
Back to contentsIt is safe to take these together. For the best results, take your vitamin D with a meal that contains some fat (like yoghurt, eggs, or avocado) to help with absorption. Probiotics can be taken at the same time or as directed on the product label.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Taking aspirin (75mg to 150mg) with Xigduo (which contains dapagliflozin and metformin) can increase the risk of your blood sugar dropping too low (hypoglycaemia). It may also increase the risk of a rare but serious condition called lactic acidosis, where too much acid builds up in your blood.

Treatment and medication
Can I take Ashwagandha and Vitamin d2 together?
There are no known significant interactions between ashwagandha and vitamin D2 (ergocalciferol). It is generally considered safe to take these two supplements together.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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