Can I take Quetiapine and Viagra connect together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking these two medicines together can cause your blood pressure to drop too low. This might make you feel dizzy, lightheaded, or faint, especially when you stand up quickly. There is also a small risk of an irregular heartbeat or a rare but serious condition called priapism (a painful erection that lasts for several hours).
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Both medicines can lower blood pressure. Quetiapine blocks certain receptors (alpha-1) that help control blood pressure, and Viagra (sildenafil) relaxes blood vessels. When used together, these effects add up. Additionally, both drugs can occasionally affect the electrical rhythm of the heart.
What you should do
Back to contentsUse this combination with caution. If you feel dizzy or lightheaded, sit or lie down immediately. Always stand up slowly from a sitting or lying position. If you experience a painful erection or one that lasts longer than 4 hours, seek emergency medical help immediately. It is best to inform your GP that you are using both of these medications.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Iron and Levothyroxine together?
Taking iron supplements at the same time as levothyroxine can significantly reduce the amount of thyroid hormone your body absorbs. This can lead to an underactive thyroid (hypothyroidism), causing symptoms like tiredness, weight gain, feeling cold, and dry skin.

Treatment and medication
Can I take Levothyroxine and Promethazine together?
There is no known direct interaction between levothyroxine and promethazine. However, if you have an overactive thyroid (hyperthyroidism), promethazine should be used with caution as it may slightly increase the risk of heart-related side effects. Since you are taking levothyroxine (usually for an underactive thyroid), this is generally only a concern if your dose is too high.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.